Are Bacteriophage viruses? Bacteriophage are actually antibodies that specialize in eating viruses, and the human body develops some resistance to them because of their presence. So, why do phages not attack the human body? The specific can look at the detailed introduction provided by this site Oh!
Is Bacteriophage a Virus?
Bacteriophage are a kind of bacteria and bacteria viruses that can “eat” bacteria, where there are bacteria, there are their whereabouts. Phages are the enemy of all bacterial fermentation plants, because they can eat almost all the beneficial bacteria in the culture, causing huge losses.
For example, when we use some beneficial bacteria in the production of antibiotics, alcohol, acetic acid, monosodium glutamate, acetone, butanol and other products, if we break into the beneficial bacteria-eating phage, these beneficial strains will be eaten up, making us waste a lot of raw materials, power and labor. That’s why engineers in pharmaceutical plants and breweries try to find ways to stop phages from entering the culture tanks.
Most Bacteriophage look like little tadpoles. Under natural environmental conditions, they can only infest bacteria and some protozoa, but not higher animals and plants.
Why Bacteriophage do not attack humans
If you eat a Bacteriophage and it enters the digestive tract, it is not considered to be in your body. If it is digested, it is no longer a phage but only a small organic molecule (amino acid, nucleic acid, etc.). The human body cannot absorb the whole phage directly, and the phage does not attack the human cells, so it cannot enter the body.
If you are referring to the case where the phage enters the bloodstream directly (e.g. direct injection or contact with a wound), I have heard of the use of phages for treatment, but the one paper I read was on how to prevent phage inactivation in the bloodstream. So under normal circumstances, Bacteriophage in the blood would be eliminated by the immune system as a “foreign body”, right?
Why Bacteriophage can fight superbugs
Superbugs are bacteria that do not respond to many antibiotics. For example, methicillin-resistant Staphylococcus aureus. Although most of its infections are mild, some:can be fatal. The phage, on the other hand, attaches to the superbug body whenever it comes into contact with the superbug.
The Bacteriophage penetrates into the body of the superbug with the help of phagocytosis by the superbug. Inside the superbacteria, the phage is decapsidized and the nucleic acid is freed. Then the phage nucleic acid is transcribed on the
information, ribonucleic acid mRNA, translated into early proteins of the phage, after which the parental phage self-replicates many daughter phage nucleic acids, and then transcribes the information ribonucleic acid from the daughter phage nucleic acids, translated into late proteins of the phage.
The phagosomes are assembled in the cytosolic paddle of the superbug to form a large number of mature phagosomes with absorbing power. When a large number of mature phage particles are accumulated in the superbug, the phage is released outside the superbug. And invade the new superbacteria. This is how superbugs are killed by phages