Bacteriophage (phage) is a general term for viruses that infect microorganisms such as bacteria, fungi, algae, actinomycetes or spirochetes, and are called phages because some of them can cause lysis of the host bacterium. They were first discovered in Staphylococcus and Shigella at the beginning of this century. As a type of virus, phages have some characteristics of viruses: they are tiny; they do not have a complete cell structure; and they contain only a single nucleic acid. It can be considered as a “predator” of bacteria. The phage genome contains many genes, but all known phages use the bacterial ribosome, various factors required for protein synthesis, various amino acids and energy production systems to grow and proliferate in the bacterial cell. Once away from the host cell, phages can neither grow nor replicate .